No. If you suspect an opioid overdose, it is safe to give naloxone. People who used opioids will then wake up and may go into withdrawal. Withdrawal is miserable, but it’s better than dying.
Naloxone does not prevent deaths caused by other drugs such as benzodiazepines (e.g. Xanax®, Klonopin® and Valium®), bath salts, cocaine, methamphetamine or alcohol. Always call 911 as an overdose victim may need other care.